The 6 Best Sheets That Don't Stain In 2022

1. The Overall Best

Mellanni’s microfiber sheets are an Amazon cult favorite and best-seller, with a 4.5-star overall rating after more than 300,000 reviews. The brushed microfiber construction is soft and silky, with a lightweight feel designed to sleep cool in the summer and warmer in the winter. In addition to being stain-resistant, it’s also wrinkle-resistant and hypoallergenic. The sheets also feature deep pockets for thicker mattresses.

One reviewer wrote: “The sheets are incredibly soft and so silky, they feel amazing on your skin. These are worth every penny, and trust me when I say you won’t want to leave your bed!!!”

Sizes: Twin, Twin XL, Full, Queen, King, Split King, California King | Colors: 42

2. A Budget-Friendly Sheet Set In 45 Colors & Patterns

Another popular hypoallergenic microfiber sheet set on Amazon, this set from Sweet Home Collection has more than 120,000 ratings and starts at a lower price point than Mellanni’s. It also comes in a wide variety of colors and patterns, including flowers, paisley, and styles inspired by block printing. Patterns in bright colors can be helpful in disguising stains, too. Soft and lightweight, the deep pockets of these sheets allow them to fit thick mattresses, and an elastic corner strap helps hold the fitted sheet in place.

One reviewer wrote: “I was skeptical about buying sheets online cause I am picky about material. I hate sheets that make me feel too hot when I sleep and I don't want anything super rough, so that makes buying online more challenging because you can't feel them before buying. However when I opened them they were absolutely perfect! They washed well and they are very very soft! They stayed cool throughout the night and the straps on the bottom were perfect to hold the fitted sheet on the bed!”

Sizes: Twin, Twin XL, Full, Queen, King, Split King, California King | Colors: 45

3. The Best For Hot Sleepers

Made from material similar to performance athletic wear, these are ultra sweat-wicking bed sheets but won’t absorb stains as quickly as cotton. Even though they are great at removing moisture, they are also designed to feel soft — not like exercise gear. Hypoallergenic and antimicrobial, they soften as you wash them. The sheets should be washed separately or with other PeachSkin sheets, and because of the quick-dry fabric, can be completely dry in 20 minutes. After more than 5,000 reviews, customers have given this an overall 4.5-star rating, with praises like: "Wonderful sheets, comfortable and stain resistant, wash well and easy to put on, fit great, will buy again when needed."

One reviewer wrote: “I want to shout from the rooftops about how much I LOVE these sheets! They are so soft and cozy without making me too hot.”

Sizes: Twin, Twin XL, Full, Full XL, Queen, King, Split King, California King | Colors: 24

4. The Best For Cold Weather

Cozy brushed polar fleece can help keep you warm in lower temperatures but is still wicking, so you shouldn’t wake up overheated or sweaty unless you're a very hot sleeper. The synthetic material is also stain-resistant and praised by reviewers for being super soft. The unique material is easy to care for and can be washed and tumble dried with like colors. The sheets are also pill-resistant, hypoallergenic, and Oeko-Tex certified to be free of harmful chemicals.

One reviewer wrote: “I am not someone who leaves reviews, so for me to leave one is a big deal. These sheets quite frankly blew my mind on their quality, comfort ,stitching,warmth,thickness and softness. I'm buying a second set. I Highly Recommend.”

Sizes: Twin, Twin XL, Full, Full XL, Queen, King, Split King | Colors: 9

5. The Best For A Silk-Like Feel

Bamboo fibers can provide a smooth finish similar to silk but without the price tag or fussy care. Here, rayon derived from bamboo is blended with stain-resistant microfiber. These sheets are also hypoallergenic and wrinkle-resistant. The only downside is that while bamboo sheets can initially feel cool, they can sleep warm and may not be the best choice for hot sleepers. However, it’s been a much-loved pick for hundreds of customers, with a 4.6-star overall rating after more than 5,000 reviews.

One reviewer wrote: “They’ve now seen almost 5 years of constant washing in our short term rental, and they’re still soft and in great shape. Pleasantly surprised at the quality!! Buying them to upgrade our primary home sheets now.”

Sizes: Twin, Full, Queen, King, California King | Colors: 12

6. These Editor-Approved Linen Sheets That Are Easy To Clean

While linen sheets aren’t typically the most stain-resistant, this set of sheets has been tested by Bustle editor Carina Finn, who has great things to say about how easy they are to care for. The sheets are not only machine washable, but they can get softer the more you wash them. Made from French flax linen, the sheets are breathable and feel cool against the skin. They come in classic white and other colors like oatmeal, dove gray, and charcoal.

Editor praise: “I love white linen sheets, and I love drinking coffee in bed — a recipe for stains. Not only are these some of the softest linen sheets I’ve ever slept on, it's also really easy to get stains out of them. I’ve been able to spot clean coffee spills with just dish soap and water, and they always come out of the washing machine looking brand new and feeling even softer than they did before.” — Carina Finn

Sizes: Full, Queen, King | Colors: 4

Also Great: An Enzyme Cleaner For Pretreating Stains

Stain-resistant sheets are, of course, not stain-proof. And while stains may come out easier from microfiber sheets, pretreating the stains that do happen can go a long way. The best kind of pretreatment for most stains on sheets is an enzyme cleaner like this one, since they’re powerful at breaking down organic materials, including most of what would typically stain sheets: blood, urine, sweat, oils, and food. The spray nozzle application of this stain remover also ensures that the bottle lasts a long time: A little goes a long way, and you can use it for up to 500 applications.

One reviewer wrote: “I have tried to remove coffee from a shirt, usually with strong soap and scrubbing. This product actually works without effort. I sprayed the large stain and when ready to do wash, I put in machine. to my amazement, after cycle finished the coffee stain was not there. Has no smell. I can't figure how it works, but it did for me.”